Cable was born with telepathic and telekinetic abilities, however, the extent to which he has been able to utilize these powers have varied dramatically throughout his appearances. Originally both were limited by his need to restrain his techno-organic infection and his powers were negligible compared to his more traditional fighting skills. However, following the subsidence of the infection they gradually increased to the point where they were similar in magnitude to those of Nate Grey, whom he is genetically identical to. At their height, he demonstrated the ability to simultaneously levitate the floating city of Providence and combat the Silver Surfer.. Following that story, his powers were burnt out and he replaced both with technological substitutes. Later he states that both his telepathy and telekinesis have faded to nothing.
During Messiah War, during the fight with his clone, Stryfe, Cable demonstrates the ability to hide others from Stryfe's mental view, implying that at least he retains some of his telepathic powers, whether he retains any telekinetic powers remains to be seen.
His techno-organic body parts possess enhanced strength and durability, and his techno-organic eye gives him enhanced eyesight, allowing him to see further than a normal human and in the infrared spectrum. He is also able to interface his techno-organic body parts with machinery, using them to hack into computers, open electronic locks, and travel through time.